In this conversation between iHerb's Global Advisor, Dr. Oz, and Dr. Darshan Shah learn about NAD+ (Nicotinamide Adenine Dinucleotide) and its role in health and longevity.

NAD+ is crucial for energy production within cells, as it is a precursor for mitochondrial energy generation. As people age, NAD+ levels decline significantly, leading to reduced energy and cellular function. This decline is accelerated by factors such as toxins, poor sleep, and inadequate nutrition.

NAD+ also plays a vital role in DNA repair through its influence on sirtuins, proteins that help maintain and repair genetic material. As NAD+ levels drop, the efficiency of DNA repair diminishes, which can lead to various health issues.

When it comes to NAD+ supplementation, products that contain Nicotinamide Riboside (NR) like those from Tru Niagen are favorable.

Dr. Shah notes that while NAD+ cannot easily enter cells due to its size and structure, NR and NMN (Nicotinamide Mononucleotide) are more effective as they can be converted into NAD+ within cells. He emphasizes that Tru Niagen has significant clinical research supporting its efficacy and is preferred over other forms due to its efficient absorption and conversion.

Dr. Shah describes the typical dosing strategy, starting with 300 mg per day and potentially increasing to 600 mg based on individual needs and responses. He also discusses lifestyle factors, such as diet, exercise, and sleep, which affect NAD+ levels. For instance, a diet high in processed foods can decrease NAD+ levels, while activities like high-intensity training and cold plunges can help boost it.

In summary, NAD+ is a critical molecule for energy production and cellular repair, and maintaining optimal levels is important for overall health. Supplementing with Nicotinamide Riboside, from reputable brands like Tru Niagen, is an effective way to support NAD+ levels, especially in the context of aging and lifestyle factors.